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Antigenic Specificity | Alpha2-Plasmin Inhititor (alpha2-PI) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 1 mL |
Concentration | n/a |
Applications | Immunodiffusion (ID),Immunoelectrophoresis (IEP),Radial Immunodiffusion (RID) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The defined antibody reactivity is restricted to alpha-2 antiplasmin as tested at the level of sensitivity of immuno-precipitation techniques. A single precipitin line is obtained in bidimensional electrophoresis, immunoelectrophoresis and double radial immunodiffusion (Ouchterlony) which shows a reaction of full identity with the purified immunogen |
Immunogen | Apha-2 antiplasmin is a single-chain glycoprotein with a molecular weight of about 65,000.The normal concentration in human plasma is 60 μ g/ml. Platelets contain significant amounts of the protein, which is released along with platelet factor 4, following thrombin stimulation. It can form 1:1 complexes with circulating plasmin. Alpha-2 antiplasmin is the most important inhibitor of plasmin-mediated fibrinolysis, but also capable of inactivating factor XIIa, kallikrein, factor XIa, thrombin and factor Xa. The importance of the alpha-2 antiplasmin as regulator of the fibrinolytic system was detected by the discovery of a congenital deficiency. Alpha-2 antiplasmin has been isolated from pooled plasma. Freund's complete adjuvant is used in the first step of the immunization procedure. |
Other Names | AI747498|Pli|Serpimf2|serpinf2|serpinf2l|wu:fd57d08|A2AP|AAP|ALPHA-2-PI|API|PLI|serpin |
Gene, Accession # | Gene ID: 5345 |
Catalog # | ABIN458040 |
Price | |
Order / More Info | Alpha2-Plasmin Inhititor (alpha2-PI) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |