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Product Name | Leptin (LEP) protein |
Description | Human leptin is a 16-kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarily in the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated, resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes and infertility. The function of leptin in regulating appetite and metabolism, as well as the possibility of using leptin as a therapeutic agent, are currently under intense investigation. Recombinant human leptin was overexpressed as insoluble protein aggregate in E. coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Alternative Names: Obesity protein, OB protein, Obesity homolog mouse protein, Leptin protein, Leptin Precursor Obesity Factor protein, Obesity factor protein, Leptin protein, LEP protein, Obese protein protein, Obesity Murine Homolog Leptin protein, Leptin Murine Obesity Homolog protein, , OBS protein |
Size | 100 µg |
Concentration | n/a |
Applications | SDS-PAGE (SDS) |
Other Names | ob|obese|LEPD|OB|OBS |
Gene, Accession, CAS # | Gene ID: 3952 |
Catalog # | ABIN934913 |
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Order / More Info | Leptin (LEP) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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