| 产品详情 |
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| Product Name | Oxotremorine M (iodide) |
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| Description | Purity >98%. Oxotremorine M is a non-selective muscarinic (M) acetylcholine receptor agonist that induces phosphoinositide hydrolysis in mouse ileum isolated from wild-type, M2, M3, and M2 /M3 knockout mice (EC50 s = 0.36, 0.52, 1.62, and 1.48 µM, respectively). It also increases M4 -induced inhibition of calcium currents in NG108-15 mouse neuroblastoma X rat glioma hybrid cells (EC50 = 0.14 µM). Oxotremorine M inhibits KCNQ2/3 potassium currents in Xenopus oocytes expressing M1 receptors and KCNQ2/3 potassium channels (IC50 = 1.1 µM). It also directly inhibits KCNQ2/3 potassium channels, decreasing KCNQ2/3 potassium currents in Xenopus oocytes lacking muscarinic receptors in a dose-dependent manner. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N,N,N-trimethyl-4-(2-oxo-1-pyrrolidinyl)-2-butyn-1-aminium, monoiodide |
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| Gene, Accession, CAS # | CAS: 713779 |
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| Catalog # | LS-H9223 |
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| Order / More Info | Oxotremorine M (iodide) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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