| 产品详情 |
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| Antigenic Specificity | Basigin (Ok Blood Group) (BSG) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 200 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Basigin (EMMPRIN, CD147) is a type I integral membrane receptor protein belonging to the immunoglobulin superfamily. Basigin is a glycosylated protein with four known isoforms, of which isoform 2 is the most abundantly expressed. Multiple functions have been ascribed to Basigin, foremost among these is stimulating the secretion of extracellular matrix metalloproteinases by adjacent fibroblasts, a function which has been implicated in promoting tumor progression. Research studies have shown that Basigin is overexpressed by many tumor cells, and its expression level may correlate with tumor malignancy. A recent study identified the BASIGIN gene as a regulatory target of Slug, suggesting a role for Basigin in the process of epithelial-mesenchymal transition. Basigin has also been identified as a marker for a subset of highly suppressive regulatory T cells , and as an obligate receptor for the malarial parasite Plasmodium falciparum on human erythrocytes.Synonyms: 5F7, CD147, EMMPRIN, M6, OK, TCSF |
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| Immunogen | Recombinant protein of human BSG |
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| Other Names | BSG|EMMPRIN|AI115436|AI325119|CD147|HT-7|5F7|M6|OK|TCSF|5A11|CE9|HT7|Ox47R|basignin|RPE7 |
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| Gene, Accession # | Gene ID: 682 |
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| Catalog # | ABIN1513833 |
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| Price | |
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| Order / More Info | Basigin (Ok Blood Group) (BSG) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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