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| Product Name | Natural Cytotoxicity Triggering Receptor 3 (NCR3) (C-Term) protein |
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| Description | Recombinant Human Natural Cytotoxicity Triggering Receptor 3/NCR3 is produced with our HEK293 expression system. The target protein is expressed with sequence (Leu19 -Thr138) of Human NCR3 fused with a FC tag at the C-terminus. Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed 'Natural Cytotoxicity Receptors'. They play a major role in triggering NK-mediated killing of most tumor cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition, NKp30 is also involved in NK-mediated induction of dendritic cell (DC) maturation. It has been demonstrated that NK cell activation signaling specifically induces lytic activity against several tumor cell types and synthesis of new NF-κB dependent proteins during the initiation of cytotoxicity. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MGC133750|1C7|CD337|LY117|MALS|NKp30|Nkp30 |
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| Gene, Accession, CAS # | Gene ID: 259197 |
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| Catalog # | ABIN1692291 |
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| Order / More Info | Natural Cytotoxicity Triggering Receptor 3 (NCR3) (C-Term) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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