| 产品详情 |
| Edit |   |
|---|
| Product Name | CD44 (CD44) (C-Term), (AA 21-220) protein |
|---|
| Description | Recombinant Human CD44 is produced by our mammalian expression system. The target protein is expressed with sequence (Gln21-Pro220) of Human CD44 fused with a FC tag at the C-terminus. CD44 is a cell-surface receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. A large number of CD44 isoforms can be generated by the insertion of different combinations of at least nine exons. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. Furthermore, an increasing quantity of evidence suggests that CD44 has various functions related to inflammatory disease. CD44 deficiency induces severe liver injury. CD44-hyaluronate mediates in lymphocyte T and monocyte adhesion to the endothelium, stimulates proinflammatory cytokine release from macrophages and participates in dedifferentiation phenotype of smooth muscle cells from contractile state to synthetic one. |
|---|
| Size | 500 µg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | AU023126|AW121933|AW146109|HERMES|Ly-24|Pgp-1|CD44A|METAA|RHAMM|CDW44|CSPG8|ECMR-III|HCELL|HUTCH-I|IN|LHR|MC56|MDU2|MDU3|MIC4|Pgp1 |
|---|
| Gene, Accession, CAS # | Gene ID: 960 |
|---|
| Catalog # | ABIN1691533 |
|---|
| Price | |
|---|
| Order / More Info | CD44 (CD44) (C-Term), (AA 21-220) protein from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|