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Product Name | CD44 (CD44) (AA 21-220) protein (His tag) |
Description | CD44 is a cell-surface receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. A large number of CD44 isoforms can be generated by the insertion of different combinations of at least nine exons. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. Furthermore, an increasing quantity of evidence suggests that CD44 has various functions related to inflammatory disease. CD44 deficiency induces severe liver injury. CD44-hyaluronate mediates in lymphocyte T and monocyte adhesion to the endothelium, stimulates proinflammatory cytokine release from macrophages and participates in dedifferentiation phenotype of smooth muscle cells from contractile state to synthetic one.Alternative Names: CD44 Antigen, CDw44, Epican, Extracellular Matrix Receptor III, ECMR-III, GP90 Lymphocyte Homing/Adhesion Receptor, HUTCH-I, Heparan Sulfate Proteoglycan, Hermes Antigen, Hyaluronate Receptor, Phagocytic Glycoprotein 1, PGP-1, Phagocytic Glycoprotein I, P |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | AU023126|AW121933|AW146109|HERMES|Ly-24|Pgp-1|CD44A|METAA|RHAMM|CDW44|CSPG8|ECMR-III|HCELL|HUTCH-I|IN|LHR|MC56|MDU2|MDU3|MIC4|Pgp1 |
Gene, Accession, CAS # | Gene ID: 960 |
Catalog # | ABIN1096318 |
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Order / More Info | CD44 (CD44) (AA 21-220) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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