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Product Name | Recombinant Mouse Interferon regulatory factor 8 (Irf8) |
Description | Purity > 90% as determined by SDS-PAGE. MW: 64.2kDa. Full Length: 1-424aa. N-terminal 6xHis-SUMO-tagged. Mus musculus (Mouse). Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune syst. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory elent, followed by cooperative binding of BATF and IRF8 and activation of genes. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Interferon consensus sequence-binding protein; ICSBP |
Gene, Accession, CAS # | Irf8, UniProt: P23611 |
Catalog # | RPC21532 |
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Order / More Info | Recombinant Mouse Interferon regulatory factor 8 (Irf8) from BIOMATIK |
Product Specific References | n/a |
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