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| Product Name | Recombinant Mouse Interferon regulatory factor 8 (Irf8) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 64.2kDa. Full Length: 1-424aa. N-terminal 6xHis-SUMO-tagged. Mus musculus (Mouse). Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune syst. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory elent, followed by cooperative binding of BATF and IRF8 and activation of genes. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Interferon consensus sequence-binding protein; ICSBP |
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| Gene, Accession, CAS # | Irf8, UniProt: P23611 |
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| Catalog # | RPC21532 |
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| Order / More Info | Recombinant Mouse Interferon regulatory factor 8 (Irf8) from BIOMATIK |
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| Product Specific References | n/a |
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