| 产品详情 |
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| Antigenic Specificity | ATG1/ULK1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ATG1/ULK1 Polyclonal Antibody. • Target Background: Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphoryla |
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| Immunogen | KLH conjugated synthetic peptide derived from human ATG1/ULK1. Immunogen Range: 1004-1050/1050 |
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| Other Names | ATG1; ATG1A; UNC51; hATG1; Unc51.1; Serine/threonine-protein kinase ULK1; Autophagy-related protein 1 homolog; Unc-51-like kinase 1; ULK1; KIAA722 |
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| Gene, Accession # | Gene ID: 8408, SwissProt: O75385 |
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| Catalog # | bs-3602R |
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| Price | |
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| Order / More Info | ATG1/ULK1 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Song, F. et al. (2013) Neurochem Int. 2013 Nov 9. PubMed: 24220541 // Gao, Yuan, et al. (2014) Chem Biol Interact. PubMed: 24887698 // Shen, P. P., et al. (2016) J Neurochem. PubMed: 27987215 // Shen et al. (2017) J.Neurochem. 140:799-813. PubMed: 27987215 |
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