| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Superoxide Dismutase 2 (Mn) (SOD2) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | chicken, cow, dog, frog, gerbil, guinea pig, hamster, human, monkey, mouse, porcine, rabbit, rana sylvatica, rat, sheep, Xenopus laevis |
|---|
| Isotype | n/a |
|---|
| Format | peroxidase (HRP) conjugate |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA,Immunohistochemistry (IHC),Immunoprecipitation (IP),Western Blotting (WB) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body. It works by catalyzing the dismutation of the superoxide radical O2Eo/oo to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2,5). In general, SODs play a major role in antioxidant defense mechanisms. There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge. The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space. SOD3 can also be distinguished by its heparin-binding capacity.Cellular Localization: Mitochondrion matrix |
|---|
| Immunogen | Human Mn SOD |
|---|
| Other Names | n/a |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | ABIN2484391 |
|---|
| Price | |
|---|
| Order / More Info | Superoxide Dismutase 2 (Mn) (SOD2) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | PubMed: 1477980, 3315461, 12736188, 2855738, 7694776 |
|---|
| 产品资料 |
|
|