| 产品详情 |
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| Antigenic Specificity | Superoxide Dismutase 2 (Mn) (SOD2) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | chicken, cow, dog, frog, gerbil, guinea pig, hamster, human, monkey, mouse, porcine, rabbit, rana sylvatica, rat, sheep, Xenopus laevis |
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| Isotype | n/a |
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| Format | antigen affinity purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | ELISA,Immunohistochemistry (IHC),Immunoprecipitation (IP),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2Eo/oo to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2,5). In general, SODs play a major role in antioxidant defense mechanisms (4). There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space (7). SOD3 can also be distinguished by its heparin-binding capacity (1).Cellular Localization: Mitochondrion matrix |
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| Immunogen | Human Mn SOD |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 399216,374042,6648,476258,100154319,281496,780457,100009336,20656,24787,100135623 |
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| Catalog # | ABIN361647 |
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| Price | |
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| Order / More Info | Superoxide Dismutase 2 (Mn) (SOD2) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 1477980, 12736188, 1661343, 2462451, 2855738, 22086848, 23067137, 7694776, 3315461, 25316288 |
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