| 产品详情 |
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| Antigenic Specificity | MAP2K3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MAP2K3 Antibody is a Rabbit Polyclonal antibody against MAP2K3. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. |
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| Immunogen | Recombinant protein of human MAP2K3. |
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| Other Names | dual specificity mitogen-activated protein kinase kinase 3; kinase MKK3; MAP kinase kinase 3; MAP2K3; MAPK/ERK kinase 3; MAPKK 3; MEK3; MP2K3; PRKMK3; MAPKK3; MEK 3; mitogen-activated protein kinase kinase 3; MKK3; Stress-activated protein kinase kinase 2; SAPK kinase 2; SAPKK-2; SAPKK2; SKK2; MAP2K3 protein; Mapk/Erk Kinase 3 Map2K3 Mek3 |
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| Gene, Accession # | MAP2K3, Gene ID: 5606, SwissProt: P46734 |
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| Catalog # | abx000737 |
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| Price | |
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| Order / More Info | MAP2K3 Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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