| 产品详情 |
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| Product Name | Lactosylceramides (bovine buttermilk) |
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| Description | A mixture of LacCers isolated from bovine buttermilk with variable N-acyl chain lengths; expressed on the plasma membrane of human phagocytes; mediates phagocytosis, chemotaxis, and superoxide generation; forms membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors; elevated levels in kidney cortex homogenates and urine are directly correlated with hyperglycemia, insulin resistance, and obesity in db/db transgenic diabetic mice; promotes recruitment of CNS-infiltrating monocytes and microglia, and enhances neurodegeneration in mice with chronic EAE, a model of MS; correlated with increased levels of pro-inflammatory cytokines IL-6, MCP-1, and MIP-1β, as well as lipids and macrophages in atherosclerotic plaques |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | LacCer |
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| Gene, Accession, CAS # | CAS: 4682-48-8 |
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| Catalog # | 27197-1 |
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| Order / More Info | Lactosylceramides (bovine buttermilk) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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