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Antigenic Specificity | RAD18 Homolog (S. Cerevisiae) (RAD18) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RAD18 is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, RAD18 is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. |
Immunogen | RAD18 antibody was raised using a synthetic peptide corresponding to a region with amino acids KQVTKVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHKRKPLPKT |
Other Names | zgc:55577|RAD18|DDBDRAFT_0218120|DDBDRAFT_0304878|DDB_0218120|DDB_0304878|DKFZp469H0810|RNF73|2810024C04Rik|Rad18sc |
Gene, Accession # | Gene ID: 56852,58186,362412 |
Catalog # | ABIN631315 |
Price | |
Order / More Info | RAD18 Homolog (S. Cerevisiae) (RAD18) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |