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Product Name | LKB1 (STK11) Recombinant protein |
Description | MW: ~85 kDa. Recombinant full-length human LKB1(STK11) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: LKB1(STK11) is a member of the serine/threonine kinase family which regulates cell polarity and functions as a tumor suppressor. STK11 is a critical barrier to pulmonary tumorigenesis which controlling initiation, differentiation, and metastasis. STK11 plays a central role in restricting HSC entry into cell cycle and in broadly |
Size | 0.02 mg, 0.05 mg |
Concentration | 0.2ug/ul |
Applications | Kinase Assay, Western Blot (WB) |
Other Names | [STK11; LKB1; PJS; STK11 Protein] |
Gene, Accession, CAS # | LKB1(STK11), Gene ID: 6794, Accession: NP_000446.1 |
Catalog # | MBS515310 |
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Order / More Info | LKB1 (STK11) Recombinant protein from MYBIOSOURCE INC. |
Product Specific References | 1. Gurumurthy, S. et.al: The Lkb1 metabolic sensor maintains haematopoietic stem cell survival. Nature 468: 659-663, 2010. Note: Erratum: Nature 476: 114 only, 2011. 2. Gan, B.et.al: Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature 468: 701-704, 2010. |
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