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Product Name | Oncomodulin (OCM) (AA 2-109) protein (His tag) |
Description | Oncomodulin-1 (OM) is a small, calcium-binding protein and a macrophage-derived growth factor, which can promote axon regeneration in retinal ganglion cells. Oncomodulin-1 is constitutively secreted by activated macrophages in the vitreous and retina in response to inflammatory conditions that promote optic nerve regeneration. Oncomodulin-1 binds RGCs with high affinity in vitro, but only when cAMP is pharmacologically elevated or if the membrane is permeabilized allowing Oncomodulin-1 access to the cytosolic compartment. Oncomodulin-1 is a member of the superfamily of calmodulin proteins and is a high-affinity calcium ion-binding protein and contains 2 EF-hand domains. OM is found in early embryonic cells in the placenta and also in tumors. It has some calmodulin-like activity with respect to enzyme activation and growth regulation.Alternative Names: Oncomodulin-1, OM, Parvalbumin Beta, OCM, OCM1, OCMN |
Size | 50 µg |
Concentration | n/a |
Applications | n/a |
Other Names | ocm1|oncm|MGC53869|MGC189033|OCM1|OM|ONCM|CBP-15|Ocm|oncmodulin|OCM2 |
Gene, Accession, CAS # | Gene ID: 654231 |
Catalog # | ABIN1097295 |
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Order / More Info | Oncomodulin (OCM) (AA 2-109) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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