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| Antigenic Specificity | Microphthalmia Transcription Factor (MITF) |
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| Clone | D5 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | Protein A/G purified |
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| Size | 0.02 mg , 7 ml , 0.1 mg , 0.1 mg , 0.2 mg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Microphthalmia Transcription Factor (MITF) Mouse Monoclonal Antibody . Reactivity: Human. Does not react with Mouse and Rat. Specificity: MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor that regulates the development and survival of melanocytes and retinal pigment epithelium, and also is involved in transcription of pigmentation enzyme genes such as tyrosinase TRP1 and TRP2. MITF has been shown to be phosphorylated by MAP kina |
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| Immunogen | NH2 terminus fragment of human Mi protein |
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| Other Names | microphthalmia-associated transcription factor isoform 4; Microphthalmia-associated transcription factor; microphthalmia-associated transcription factor; melanogenesis associated transcription factor; Class E basic helix-loop-helix protein 32; bHLHe32, MITF; MITF; MI; WS2; CMM8; WS2A; bHLHe32; BHLHE32; bHLHe32 |
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| Gene, Accession # | MITF, Gene ID: 4286, NCBI: NP_000239.1, UniProt: O75030 |
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| Catalog # | MBS438955 |
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| Price | |
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| Order / More Info | Microphthalmia Transcription Factor (MITF) Antibody from MYBIOSOURCE INC. |
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| Product Specific References | Hemesath P, et. al. MAP kinase links the transcription factor microphthalmia to c-Kit signalling in melanocytes. Nature. 1998, 391:298-301 Weilbaecher KN, et. al. Age-resolving osteopetrosis: a rat model implicating microphthalmia and the related transcription factor TFE3. J. Exp.Med. 1998, 187: 775-78 |
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