产品名称 NOTCH3 Antibody from ABBEXA
产品货号 abx000900
产品价格 现货询价,电话:010-67529703
产品规格 50 µl, 100 µl, 200 µl
产品品牌 ABBEXA
产品概述
产品详情
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Antigenic SpecificityNOTCH3
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formataffinity purified
Size50 µl, 100 µl, 200 µl
Concentration> 1 mg/ml
ApplicationsWB. RUO
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DescriptionNOTCH3 Antibody is a Rabbit Polyclonal antibody against NOTCH3. NOTCH3 belongs to the NOTCH family. It functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus. NOTCH3 affects the implementation of differentiation, proliferation and apoptotic programs. Defects in NOTCH3 are the cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). The antibody is specific to NOTCH3.
ImmunogenA synthetic peptide of human NOTCH3.
Other NamesADASIL; CASIL; CADASIL; Neurogenic locus notch homolog protein 3; Notch 3; NOTCH3; Neurogenic locus notch homolog protein 3Notch 3; Notch 3 extracellular truncation; Notch 3 intracellular domain; Notch homolog 3 (Drosophila); HGNC:7883; Notch (Drosophila) homolog 3; Notch homolog 3
Gene, Accession #NOTCH3, Gene ID: 4854, SwissProt: Q9UM47
Catalog #abx000900
Price
Order / More InfoNOTCH3 Antibody from ABBEXA
Product Specific Referencesn/a
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