| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | NOTCH3 |
|---|
| Clone | monoclonal |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 80 µl, 400 µl |
|---|
| Concentration | n/a |
|---|
| Applications | WB. RUO |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq]. This NOTCH3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 2291-2321 amino acids from the C-terminal region of human NOTCH3. |
|---|
| Immunogen | Human NOTCH3. |
|---|
| Other Names | ADASIL; CASIL; CADASIL; Neurogenic locus notch homolog protein 3; Notch 3; NOTCH3; Neurogenic locus notch homolog protein 3Notch 3; Notch 3 extracellular truncation; Notch 3 intracellular domain; Notch homolog 3 (Drosophila); HGNC:7883; Notch (Drosophila) homolog 3; Notch homolog 3 |
|---|
| Gene, Accession # | SwissProt: Q9UM47 |
|---|
| Catalog # | abx025429 |
|---|
| Price | |
|---|
| Order / More Info | NOTCH3 Antibody from ABBEXA |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|