| 产品详情 |
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| Antigenic Specificity | NOTCH1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB, IF/ICC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NOTCH1 Antibody is a Rabbit Polyclonal antibody against NOTCH1. This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development. |
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| Immunogen | Recombinant protein of human NOTCH1. |
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| Other Names | hN1; TAN1; Notch homolog 1; translocation-associated (Drosophila); NOTCH1; Neurogenic locus notch homolog protein 1; Notch 1; Translocation-associated notch protein TAN-1 |
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| Gene, Accession # | NOTCH1, Gene ID: 4851, SwissProt: P46531 |
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| Catalog # | abx001906 |
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| Price | |
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| Order / More Info | NOTCH1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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