| 产品详情 |
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| Product Name | 4-iodo-SAHA |
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| Description | Purity >98%. 4-iodo-SAHA is a hydrophobic derivative of the class I and class II histone deacetylase (HDAC) inhibitor SAHA. At 1 µM it demonstrates >60% inhibition of HDAC1 and HDAC6 activity in a deacetylase activity assay, similar to that of SAHA. 4-iodo-SAHA inhibits proliferation of SK-BR-3 breast-derived and HT29 colon-derived cell lines with EC50 values comparable to that of SAHA (1.1 and 0.95 µM versus 2.1 and 2 µM, respectively). It is 10-fold more potent as an inhibitor of U937 leukemia cell proliferation compared to SAHA (0.12 µM versus 1.2 µM, respectively). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N1-hydroxy-N8-(4-iodophenyl) octanediamide |
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| Gene, Accession, CAS # | CAS: 1219807-87-0 |
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| Catalog # | LS-H6131 |
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| Price | |
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| Order / More Info | 4-iodo-SAHA from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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