| 产品详情 |
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| Antigenic Specificity | Bone Morphogenetic Protein 7 (BMP7) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bone morphogenetic proteins (BMPs) were first identified as molecules that can induce ectopic bone and cartilage formation . BMPs belongs to the TGF-beta superfamily, playing many diverse functions during development . BMPs are synthesized as precursor proteins and then processed by cleavage to release the c-terminal mature BMP. BMPs initiate signaling by binding to a receptor complex containing type I and type II serine/threonine receptor kinases that then phosphorylate Smad (mainly Smad1, 5 and 8), resulting the translocation of Smad into the nucleus. BMP was also reported to activate MAPK pathways in some systems . BMP7, also known as osteogenic protein-1 (OP-1), is found to be upregulated in some cancer cells , and may play a role in cancer metastasis . Synonyms: BMP7,OP-1 , |
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| Immunogen | Recombinant protein of human BMP7 |
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| Other Names | bmp-7|bmp7|op-1|BMP7|zgc:153025|OP-1|OP1|BMP-7|fb83f09|wu:fb83f09 |
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| Gene, Accession # | Gene ID: 655,12162,85272 |
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| Catalog # | ABIN1683412 |
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| Price | |
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| Order / More Info | Bone Morphogenetic Protein 7 (BMP7) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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