产品详情 |
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Antigenic Specificity | APC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl |
Concentration | n/a |
Applications | WB. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. This APC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1148-1176 amino acids from the Central region of human APC. |
Immunogen | Human APC. |
Other Names | Adenomatosis Polyposis Coli Protein; APC; DP2; DP2.5; DP3; FAP; FPC; GS; Deleted in polyposis 2.5; APC protein; Adenomatous polyposis coli protein; mAPC; Protein APC |
Gene, Accession # | APC, SwissProt: P25054 |
Catalog # | abx030900 |
Price | |
Order / More Info | APC Antibody from ABBEXA |
Product Specific References | n/a |
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