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Product Name | Interferon gamma (IFNG) (Active) protein |
Description | Interferon-gamma (IFN-gamma, also known as Type II interferon or immune interferon) is a cytokine produced primarily by T-lymphocytes and natural killer cells. The protein shares no significant homology with IFN-beta or the various IFN-alpha family proteins. Mature IFN-gamma, exists as noncovalently-linked homodimers. Human IFN-gamma, is highly species specific and is biologically active only in human and primate cells.IFN-gamma, was originally characterized based on its antiviral activities. The protein also exerts antiproliferative, immunoregulatory and proinflammatory activities and is thus important in host defense mechanisms. IFN-gamma, induces the production of cytokines, upregulates the expression of class I and II MHC antigens, Fc receptor and leukocyte adhesion molecules. It modulates macrophage effector functions, influences isotype switching and potentiates the secretion of immunoglobulins by B cells. IFN-gamma, also augments TH1 cell expansion and may be required for TH1 cell differentiation. Synonym: Interferon-gamma ( IFN-gamma, ), Rat. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4. |
Size | 1 mgi3/4 |
Concentration | n/a |
Applications | n/a |
Other Names | IFNG2|IFN-g|Ifg|IFN-G|IFN-gamma|IFNG|IFG|IFI |
Gene, Accession, CAS # | Gene ID: 25712 |
Catalog # | ABIN987998 |
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Order / More Info | Interferon gamma (IFNG) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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