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| Product Name | Interferon gamma (IFNG) (Active) protein |
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| Description | Human Interferon gamma (hIFN-γ) is amacrophage-activating factor and the lone member of Interferon type II.The active form of IFN-γ is an antiparallel dimer that interacts with the receptor IFN-γR1 and sets off IFN-γ/JAK/STAT pathway. IFN-γ signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity. While IFN-γ-induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN-γ is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers. Recombinant human Interferon gamma (rhIFN-γ) produced in E. coli is a non-glycosylated polypeptide chain of 144 amino acids. A fully biologically active molecule, rhIFN-γ has a molecular mass of 17 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary refolding and chromatographic techniques.Synonyms: Immune Interferon, type II interferon, T cell interferon, MAF, IFNG, IFG, IFI,IFN-gamma. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IFNG2|IFN-g|Ifg|IFN-G|IFN-gamma|IFNG|IFG|IFI |
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| Gene, Accession, CAS # | Gene ID: 3458 |
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| Catalog # | ABIN2018003 |
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| Order / More Info | Interferon gamma (IFNG) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 1902591, 20837696, 14525967, 19161415, 17768067 |
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