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| Product Name | Interferon gamma (IFNG) (AA 23-155) (Active) protein |
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| Description | Sharing 41% sequence identity with human Interferon gamma (hIFN--γ), mouse IFN gamma (mIFN--γ) is a macrophage-activating factor.The active form of IFN--γ is an antiparallel dimer that sets off IFN--γ/JAK/STAT pathway. IFN--γ signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity.While IFN--γ-induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN--γ is also implicated in resistance to NK cell and CTL responses and in immune escape in avariety of cancers. Recombinant mouse IFN gamma (rmIFN-γ) produced in E. coli is a non-glycosylated polypeptide chain of 134 amino acids. A fully biologically active molecule, rmIFN--γ has a molecular mass of 15 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary refolding and chromatographic techniques.Synonyms: Type II interferon, T cell interferon, MAF, IFNG, IFG, IFI |
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| Size | 20 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IFNG2|IFN-g|Ifg|IFN-G|IFN-gamma|IFNG|IFG|IFI |
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| Gene, Accession, CAS # | Gene ID: 15978 |
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| Catalog # | ABIN2018008 |
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| Order / More Info | Interferon gamma (IFNG) (AA 23-155) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 1902591, 20837696, 14525967, 19161415, 17768067 |
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