| 产品详情 |
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| Product Name | BVT 948 |
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| Description | A cell-permeable inhibitor of PTPs (IC50s = 0.09-1.7 µM) through oxidation of the catalytic cysteine residue; inhibits redox-sensitive CYP isoforms with IC50 values less than 10 µM; inhibits the protein methyltransferases SETD8, SETD2, G9a, SMYD2, CARM1, and PRMT3 with IC50 values from 0.7 to 3.2 µm |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | biochemical inhibitor cytochrome P450 phosphatase methyltransferase epigenetic histone modification diabetes cancer neuroscience intracellular signaling BVT948 inhibit protein tyrosine phosphatase noncompetitive cell-permeable PTP facilitate oxidation catalytic cysteine residue hydrogen peroxide redox-sensitive CYP450 isoform insulin tolerance ob/ob obese/obese mice mouse suppress expression matrix metalloproteinase-9 MMP-9 MMP9 invasion breast increase NMDA-induced N-Methyl-D-aspartic acid N-Methyl-D-aspartate substance P release spinal cord slice |
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| Gene, Accession, CAS # | CAS: 39674-97-0 |
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| Catalog # | 16615-10 |
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| Price | |
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| Order / More Info | BVT 948 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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