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| Product Name | Recombinant Human Integrin-linked protein kinase |
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| Description | 1-228aa; Partial. MW: 30.1kD. Purity >90% as determined by SDS-PAGE. Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithel |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [59 kDa serine/threonine-protein kinase; ILK-1; ILK-2; p59; ILK] |
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| Gene, Accession, CAS # | ILK, Gene ID: 3611, Accession: NP_001014794.1 |
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| Catalog # | MBS1265396 |
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| Order / More Info | Recombinant Human Integrin-linked protein kinase from MYBIOSOURCE INC. |
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| Product Specific References | Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase.Hannigan G.E., Leung-Hagesteijn C., Fitz-Gibbon L., Coppolino M.G., Radeva G., Filmus J., Bell J.C., Dedhar S.Nature 379:91-96(1996) Cloning of an isoform of integrin-linked kinase (ILK) that is upregulated in HT-144 melanoma cells following TGF-beta1 stimulation.Janji B., Melchior C., Vallar L., Kieffer N.Oncogene 19:3069-3077(2000) Integrin-linked kinase genomic sequence.Tadic B., Hannigan |
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