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| Product Name | Recombinant Hadronyche versuta Omega-hexatoxin-Hv1a |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 20.1kDa. Full Length: 1-37aa. N-terminal 6xHis-SUMO-tagged. Hadronyche versuta (Blue mountains funnel-web spider) (Atrax versutus). Reversibly and voltage-independently blocks both mid-low- (M-LVA) and high-voltage-activated (HVA) calcium channels in cockroach DUM neurons. Lethal to many insect orders but not toxic to mice or rabbits. May target the insect high-voltage-activated calcium channel Dmca1D. Also inhibits acarines calcium channels. An extremely high toxin concentration partially inhibits Cav1.2/CACNA1C, Cav2.1/CACNA1A and Cav2.2/CACNA1B calcium channel of rats. As for omega-AcTx-Hv2a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Omega-atracotoxin-Hv1a; AcTx-Hv1; Omega-AcTx-Hv1a |
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| Gene, Accession, CAS # | UniProt: P56207 |
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| Catalog # | RPC22635 |
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| Order / More Info | Recombinant Hadronyche versuta Omega-hexatoxin-Hv1a from BIOMATIK |
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| Product Specific References | n/a |
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