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Product Name | Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L5 |
Description | 1-326aa; Full Length of Isoform 4. MW: 53.3kD. Purity >90% as determined by SDS-PAGE. Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1. |
Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
Concentration | n/a |
Applications | n/a |
Other Names | [Ubiquitin C-terminal hydrolase UCH37; Ubiquitin thioesterase L5] |
Gene, Accession, CAS # | UCHL5, Gene ID: 51377, Accession: NP_001186190.1 |
Catalog # | MBS969628 |
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Order / More Info | Recombinant Human Ubiquitin carboxyl-terminal hydrolase isozyme L5 from MYBIOSOURCE INC. |
Product Specific References | Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1.Yao T., Song L., Xu W., De;Martino G.N., Florens L., Swanson S.K., Washburn M.P., Conaway R.C., Conaway J.W., Cohen R.E.Nat. Cell Biol. 8:994-1002(2006) |
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