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| Product Name | Recombinant Human Ubiquitin-conjugating enzyme E2 D3 |
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| Description | 1-147aa; Full Length. MW: 32.7kD. Purity >90% as determined by SDS-PAGE. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'-linked polyubiquitination. Cooperates with the E2 CDC34 and the SCF(FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation. Acts as an initiator E2, priming the phosphorylated NFKBIA target at positions 'Lys-21' and/or 'Lys- |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Ubiquitin carrier protein D3; Ubiquitin-conjugating enzyme E2(17)KB 3; Ubiquitin-conjugating enzyme E2-17 kDa 3; Ubiquitin-protein ligase D3] |
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| Gene, Accession, CAS # | UBE2D3, Gene ID: 7323, Accession: NP_003331.1 |
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| Catalog # | MBS954971 |
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| Order / More Info | Recombinant Human Ubiquitin-conjugating enzyme E2 D3 from MYBIOSOURCE INC. |
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| Product Specific References | Identification of a family of closely related human ubiquitin conjugating enzymes.Jensen J.P., Bates P.W., Yang M., Vierstra R.D., Weissman A.M.J. Biol. Chem. 270:30408-30414(1995) |
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