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| Antigenic Specificity | Chemokine (C-X-C Motif) Ligand 2 (CXCL2) (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GRO (Growth Related Oncogene) belonging to the IL8 family is a polypeptide which has three isoforms alpha, beta and gamma, and it inhibits proliferation of endothelial cells. GRO/CINC1 (cytokine-induced neutrophil chemo attractant 1) was originally purified from media conditioned by IL1 beta stimulated rat kidney epithelioid cells (NRK52E). The amino acid sequence that encodes rat CINC1 was identified in 1989 by Watanabe's group at Toyama Medical and Pharmaceutical University. CINC1 is a member of the alpha (CXC) subfamily of chemokines. Three additional rat CXC chemokines (CINC2 alpha, CINC2 beta, CINC3/MIP2) have been identified. The protein sequence of CINC1 is 63-67% identical to that of CINC2 alpha, CINC2 beta and CINC3/MIP2. In addition, each of GRO alpha, GRO beta and GRO gamma is sharing 68%, 71% and 69% identity respectively with CINC1. It has been suggested that CINCs are the rat counterparts of human GROs. GRO alpha/MGSA has a high homology with IL8 in amino acid sequences. It has been reported that it also has a similar configuration in 3D structural analysis and almost the same level of leukocyte chemotaxis with IL8. Also its production from activated monocyte, fibroblast, epithelial and endothelial cells has been reported. It has been reported that GRO beta inhibits angiogenesis in case of administration of GRO in vivo. Mouse KC (Keratinocyte-derived Cytokine) is a counterpart of human GRO protein and it has been reported that KC is produced in such as activated monocyte and fibroblast. Mouse MIP (Macrophage Inflammatory Protein) is polypeptide which has leukocyte chemotaxis and it originally was discovered as a small protein (molecular weight about 8 kDa) induced by the lipopolysaccharide stimulation in the macrophage cell line. Two kinds, MIP1 and MIP2 are identified by the research afterwards. Description: Serum. Synonyms: Polyclonal MIP2 antibody, Anti-MIP2 antibody, MIP-2 antibody, Viral Macrophage inflammatory antibody-2 antibody. |
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| Immunogen | MIP2 antibody was raised in rabbit using a synthetic peptide corresponding to the CTerminal of murine MIP2 as the immunogenSerum |
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| Other Names | GRO3|MIP-2alpha|Mip-2|Scyb2|CINC-2a|GRO2|GROb|MGSA-b|MIP-2a|MIP2|MIP2A|SCYB2|Gro2|MIP-2|Mgsa-b|Mip2|Scyb|GROB|GROX|CDW2|GID7 |
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| Gene, Accession # | Gene ID: 20310 |
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| Catalog # | ABIN927204 |
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| Price | |
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| Order / More Info | Chemokine (C-X-C Motif) Ligand 2 (CXCL2) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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