| 产品详情 |
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| Product Name | Nicotinamide phosphoribosyltransferase (NAMPT) (AA 1-491) (Active) protein (His tag) |
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| Description | Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | SDS-PAGE (SDS) |
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| Other Names | PBEF1|pbef|pbef1|1110035O14Rik|PBEF|VF|VISFATIN|AI314458|AI480535|NAmPRTase|Pbef|Pbef1|Visfatin|visfatin |
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| Gene, Accession, CAS # | Gene ID: 10135 |
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| Catalog # | ABIN1344091 |
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| Order / More Info | Nicotinamide phosphoribosyltransferase (NAMPT) (AA 1-491) (Active) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 17123517, 23536823 |
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