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| Product Name | Fas (TNF Receptor Superfamily, Member 6) (FAS) (AA 26-172) (Active) protein |
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| Description | Fas Receptor and Fas Ligand (FasL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively. Binding of FasL to Fas triggers apoptosis in Fas-bearing cells. The mechanism of apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms. These active caspases then cleave various cellular substrates leading to the eventual cell death. sFasR is capable of inhibiting FasL-induced apoptosis by acting as a decoy receptor that serves as a sink for FasL.Synonyms: soluble Fas receptor (sFasR), TNFRSF6, CD95, Apo I, Fas Antigen |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AI196731|APO1|APT1|CD95|TNFR6|Tnfrsf6|lpr|TNFRSF6|ALPS1A|APO-1|FAS1|FASTM|A630082H08Rik|FAS |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN2017774 |
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| Order / More Info | Fas (TNF Receptor Superfamily, Member 6) (FAS) (AA 26-172) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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