| 产品详情 |
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| Antigenic Specificity | Lamin A/C |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100 ul |
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| Concentration | n/a |
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| Applications | ICC, IF, IP, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit polyclonal antibody to lamin A/C also known as Renal carcinoma antigen NY-REN-32 whose expression can be detected in the arteries. It is highly expressive in the greater omentum and is found in the nucleoplasm. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence. This protein plays an extensive role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics but is also required for normal development of the peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. |
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| Immunogen | A peptide mapping at the N-terminus of Lamin A/C of human origin. |
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| Other Names | 70 kDa lamin, Cardiomyopathy dilated 1A (autosomal dominant), CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, Lamin A, Lamin A/C, Lamin A/C like 1, Lamin, Lamin C, Lamin-A/C, LDP1, LFP, LGMD1B, Limb girdle muscular dystrophy 1B (autosomal dominant), LMN 1, LMN A, LMN C, LMN1, LMNA, LMNA_HUMAN, LMNC, LMNL1, Prelamin A/C, PRO1, Renal carcinoma antigen NY REN 32, Renal carcinoma antigen NY-REN-32, Renal carcinoma antigen NYREN32 |
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| Gene, Accession # | UniProt: P02545 |
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| Catalog # | orb378962 |
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| Price | |
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| Order / More Info | Lamin A/C Antibody from BIORBYT LTD. |
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| Product Specific References | n/a |
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