| 产品详情 |
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| Antigenic Specificity | CD81 Molecule (CD81) |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | mouse |
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| Isotype | IgG1 |
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| Format | fluorescein (FITC) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ABIN134045reacts with the extracellular loops of murine CD81 (TAPA- 1) molecule. As a member of the tetraspanin superfamily of cell-surface proteins, CD81 has been linked to the control of cell proliferation, adhesion and motility. CD81 is expressed in higher levels on resting murine B cells than on resting T cells and is functionally active on B cells as it induces homotypic adhesion of B lymphocytes. Unlike human CD81, which is expressed equally on all thymocytes, murine CD81 is upregulated on CD4 CD8 thymocytes, then down-regulated again on mature single-positive thymocytes. Murine dendritic cells, splenic macrophages and NK cells all express very high levels of CD81. CD81 has also been involved in the induction of IL-4 secretion from T cells during Th2 immune responses. It has been reported that CD81 expression can also be induced in mature T cells upon activation. This anti-CD81 mAb has been shown to decrease the proliferation of LPS stimulated CD81 +/+ B cells to levels similar to that of CD81 -/- B cells. |
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| Immunogen | n/a |
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| Other Names | Tapa-1|Tapa1|Tspan28|CVID6|S5.7|TAPA1|TSPAN28 |
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| Gene, Accession # | Gene ID: 12520 |
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| Catalog # | ABIN134045 |
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| Price | |
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| Order / More Info | CD81 Molecule (CD81) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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