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| Product Name | Recombinant Mouse Scavenger receptor cysteine-rich type 1 protein M130 (Cd163), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 32.2kDa. Partial: 86-365aa. N-terminal 6xHis-tagged. Mus musculus (Mouse). Involved in clearance and endocytosis of hoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hoglobin/haptoglobin and subsequent breakdown of he. Binds hoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.After shedding, the soluble form (sCD163) may play an anti-inflammatory role. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | CD163 |
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| Gene, Accession, CAS # | Cd163, UniProt: Q2VLH6 |
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| Catalog # | RPC25383 |
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| Order / More Info | Recombinant Mouse Scavenger receptor cysteine-rich type 1 protein M130 (Cd163), partial from BIOMATIK |
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| Product Specific References | n/a |
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