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Product Name | Capping Protein (Actin Filament), Gelsolin-Like (CAPG) (AA 1-348) protein |
Description | CAPG is part of the gelsolin/villin family of actin-regulatory proteins. CAPG reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated method, though it does not separate preformed actin filaments. By capping the barbed ends of actin filaments, CAPG contributes to the control of actin-based motility in non-muscle cells. CAPG is involved in macrophage function. CAPG is involved in regulating cytoplasmic and/or nuclear structures via possible interactions with actin. CAPG binds DNA. CAPG lacks a nuclear export sequence present in structurally related proteins. CAPG is a tumor suppressor protein that plays a role in the tumorigenic progression of certain cancers. Dysregulated expression of CAPG was found in premalignant and malignant oral carcinogenesis Synonyms: AFCP, CAPG, Macrophage-capping protein, Actin regulatory protein CAP-G, MCP |
Size | 5 µg |
Concentration | n/a |
Applications | n/a |
Other Names | AFCP|MCP|gCap39|mbh1 |
Gene, Accession, CAS # | Gene ID: 822 |
Catalog # | ABIN807650 |
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Order / More Info | Capping Protein (Actin Filament), Gelsolin-Like (CAPG) (AA 1-348) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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