| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Keratin 8 (KRT8) (aa 127-145), (N-Term) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | immunogen affinity purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Cytokeratin 8(CK8), also known as Keratin 8(K8), is a type II keratin. Among the various intermediate filament(IF) proteins, cytokeratin 8(CK8) is especially remarkable as it is produced early in embryogenesis, is the only type-II CK occurring in many simple epithelial cells, and can also be synthesized in certain non-epithelial cells. Cytokeratin 8 mRNA was abundant in fetal small intestine, placenta, pancreas, lung, liver, and kidney. Levels of cytokeratin 8 mRNA in placenta increased slightly during pregnancy. He et al.(2002) presented evidence that K8 is a new cytoplasmic target for JNK in Fas receptor-mediated signaling. The functional significance of this phosphorylation could relate to regulation of JNK signaling and/or regulation of keratin dynamics. |
|---|
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human Cytokeratin 8(127-145aa QQQKTARSNMDNMFESYIN), different from the related rat and mouse sequences by one amino acid. |
|---|
| Other Names | ck8|cyk8|k2c8|card2|krt2-5|MGC69490|KRT8|DKFZp468F2127|CARD2|CK-8|CK8|CYK8|K2C8|K8|KO|KRT2-8|AA960620|AL022697|AU019895|Card2|EndoA|Krt-2.8|Krt2-8|CYKER|DreK8|cb186|krt2-8|sb:cb186|wu:fa20h05|wu:fa95h10|wu:fb96c06|zf-K8|zfk8|KERATIN8 |
|---|
| Gene, Accession # | Gene ID: 3856 |
|---|
| Catalog # | ABIN343360 |
|---|
| Price | |
|---|
| Order / More Info | Keratin 8 (KRT8) (aa 127-145), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | PubMed: 1691124, 1692965, 11781324 |
|---|
| 产品资料 |
|
|