产品详情 |
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Antigenic Specificity | Cathepsin D (CTSD) (aa 21-412) |
Clone | P4G2AT |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA,Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cathepsin D is synthesized as a 54 kDa precursor, which is proteolytically processed to an intermediate 44 kDa single chain, which matures into more stable 34 kDa and 14 kDa two chain form. It is an estrogen-regulated lysosomal protease that has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix, and xonnective tissue. Because of its mitogenic and proteolytic activities, it has been implicated as a prognostic marker in many tumor types. Cathepsin D is expressed in epithelial cells as well as in macrophagesSynonyms: Cathepsin D, EC 3.4.23.5, CTSD, CPSD, CLN10, MGC2311 |
Immunogen | Anti-human CTSD mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CTSD AA 21-412 |
Other Names | catD|fb93e11|fj17b09|wu:fb93e11|wu:fj17b09|LOC398557|Cathd|CatD|LOC100136761|CTSD|DKFZp469J0315|DDBDRAFT_0205785|DDBDRAFT_0215012|DDB_0205785|DDB_0215012|CLN10|CPSD|CD |
Gene, Accession # | Gene ID: 1509 |
Catalog # | ABIN808556 |
Price | |
Order / More Info | Cathepsin D (CTSD) (aa 21-412) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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