| 产品详情 |
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| Product Name | Recombinant Human Tumor necrosis factor receptor superfamily member 6 protein (FAS) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE and HPLC. MW: 17.6kDa. Partial: 17-173aa. tag-Free. Homo sapiens (Human). Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). {ECO:0000269|PubMed:19118384, ECO:0000269|PubMed:7533181}. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Apo-1 antigen, FASLG receptor, CD antigen CD95 |
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| Gene, Accession, CAS # | FAS,APT1,FAS1,TNFRSF6, UniProt: P25445 |
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| Catalog # | RPC26713 |
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| Price | |
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| Order / More Info | Recombinant Human Tumor necrosis factor receptor superfamily member 6 protein (FAS) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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