| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | delta-Like 1 Homolog (Drosophila) (DLK1) |
|---|
| Clone | 24-11-14 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG1 |
|---|
| Format | fluorescein (FITC) conjugate |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FACS) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Delta like protein (Dlk), also known as Preadipocyte factor-1 (Pref-1) or zona glomerulosa-specific factor (ZOG), is an EGF-like transmembrane protein expressed preadipocytes but not in mature adipocytes. It is highly expressed in fetal liver, the adrenal gland, and placenta, as well as some neuroendocrine tumors and small cell lung carcinomas, where it plays a role in differentiation and proliferation. Dlk positively and negatively regulates adipocyte differentiation via at least four major variants (45-60 kDa) of Dlk generated by alternatively splicing. Constitutive expression of Dlk inhibits adipogenesis, but insulin or insulin like growth factor-1 (IGF-1) can circumvent this inhibition. Regulated processing of Dlk releases a 50 kDa soluble form that was previously characterized as Fetal Antigen-1, a protein involved in pancreatic island cell differentiation.Synonyms: DLK, DLK-1, PREF1, Preadipocyte factor 1, Protein delta homolog 1, pG2 |
|---|
| Immunogen | Pref-1-Fc protein |
|---|
| Other Names | DLK|DLK-1|Delta1|FA1|PREF1|Pref-1|ZOG|pG2|AW742678|DlkI|Ly107|Peg9|SCP1|pref-1|Zog |
|---|
| Gene, Accession # | Gene ID: 13386 |
|---|
| Catalog # | ABIN2853604 |
|---|
| Price | |
|---|
| Order / More Info | delta-Like 1 Homolog (Drosophila) (DLK1) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|