| 产品详情 |
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| Antigenic Specificity | COL18A1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 100ug (sample available) |
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| Concentration | 0.5-1mg/ml, actual concentration varies by lot. |
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| Applications | ELISA, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal Picoband™ antibody for COL18A1 detection. Tested with WB, ELISA(Cap) in Human;Mouse;Rat. No cross reactivity with other proteins. Collagen alpha-1(XVIII) chain is a protein that in humans is encoded by the COL18A1 gene. This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants. |
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| Immunogen | E. coli-derived human COL18A1 recombinant protein (Position: H1572-K1754). |
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| Other Names | Collagen alpha-1(XVIII) chain; Endostatin; COL18A1 |
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| Gene, Accession # | COL18A1, UniProt: P39060 |
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| Catalog # | A01302-1 |
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| Price | |
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| Order / More Info | COL18A1 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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