产品名称 delta-Like 1 (DLL1) (aa 168-184), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN1673390
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
Edit&nbsp
Antigenic Specificitydelta-Like 1 (DLL1) (aa 168-184), (N-Term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size100 µg
Concentrationn/a
ApplicationsWestern Blotting (WB)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionDLL1(DELTA-LIKE 1) also known as DL1 or DELTA1, is a protein that in humans is encoded by the DLL1 gene. DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. Using FISH, Gray et al.(1999) mapped the DLL1 gene to chromosome 6q27, near a locus for type I diabetes. Functional analysis by Han et al.(2000) suggested that a soluble fusion protein containing the DSL domain of DLL1 and its adjacent 50 N-terminal amino acids increased the viability of hemopoietic cells but inhibited cell death. Jaleco et al.(2001) used a cell coculture assay to show that DLL1 blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. In contrast, JAG1 did not disturb either B-cell or T-cell/NK-cell development. Galceran et al. found that mouse Lef1 bound multiple sites in the Dll1 promoter in vitro and in vivo, and mutation of the Lef1 sites impaired expression of a reporter transgene in the presomitic mesoderm of embryonic mice.
ImmunogenA synthetic peptide corresponding to a sequence at the N-terminus of human DLL1(168-184aa RTDLKYSYRFVCDEHYY), different from the related rat and mouse sequences by one amino acid.
Other NamesX-delta-1|XDelta1|Xdelta-1|delta|delta-1|delta1|x-delta|DLL1|CRLM2|Ly114|Tpte2|Tslpr|DELTA1|DL1|Delta|Delta1
Gene, Accession #Gene ID: 28514
Catalog #ABIN1673390
Price
Order / More Infodelta-Like 1 (DLL1) (aa 168-184), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific ReferencesPubMed: 10079256, 10688816, 11581320
产品资料