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| Product Name | MICA BioAssay™ ELISA Kit, Human |
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| Description | Sandwich ELISA quantitative detection kit for Human MICA in cell culture supernates, cell lysates, tissue homogenates and serum. MHC class I polypeptide-related sequence A is a protein that in humans is encoded by the MICA gene.1 The MICA gene encodes a 383-amino acid polypeptide with a predicted mass of 43kD.The MICA and MICB genes occur in a 200-kb region spanning the TNFA and TNFB cluster at 6p21.3.2 MICA and the closely related MICB were recognized by intestinal epithelial T cells expressing diverse V-delta-1 gamma/delta TCRs.3 The MICA protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is further distinguished by its unusual exon-intron organization and preferential expression in fibroblasts and epithelial cells. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by NK cells, NKT cells, and most of the subtypes of T cells. MICA and other members |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 4276, SwissProt: Q29983 |
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| Catalog # | 143967 |
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| Order / More Info | MICA BioAssay™ ELISA Kit, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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