| 产品详情 |
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| Antigenic Specificity | Tryptophan Hydroxylase 1 (TPH1) |
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| Clone | polyclonal |
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| Host Species | Sheep |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (Frozen Sections) (IHC (fro)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Tryptophan hydroxylase (TPH) catalyzes the first step in the biosynthesis of serotonin and melatonin (Martinez et al., 2001). Thus, expression of TPH can be used as an indicator of the localization of serotonin and melatonin in brain. In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland (Haycock et al., 2002) . Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis (Martinez et al., 2001). Anti-Tryptophan Hydroxylase Western blot of human dorsal Raphe nucleus showing specifc immunolabeling of the ~55k tryptophan hydroxylase protein. |
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| Immunogen | n/a |
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| Other Names | tph|tph1|tphD1|TPH|LOC100229598|TPRH|TRPH|Tph|SERGEF |
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| Gene, Accession # | Gene ID: 21990,24848,7166,387560,100101558,395799,611956,781941 |
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| Catalog # | ABIN361412 |
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| Price | |
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| Order / More Info | Tryptophan Hydroxylase 1 (TPH1) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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