| Edit |   |
|---|
| Antigenic Specificity | MBD3 |
|---|
| Clone | 5C3 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100ul |
|---|
| Concentration | n/a |
|---|
| Applications | WB |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | MBD3 (5C3) Monoclonal Antibody. • Target Background: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases. |
|---|
| Immunogen | Purified His-tagged MBD3 protein was used to produced this monoclonal antibody. |
|---|
| Other Names | Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3; MBD3 |
|---|
| Gene, Accession # | Gene ID: 53615, SwissProt: O95983 |
|---|
| Catalog # | bsm-51226M |
|---|
| Price | |
|---|
| Order / More Info | MBD3 Antibody from BIOSS ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|