| 产品详情 |
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| Antigenic Specificity | MBD2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | serum |
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| Size | 100ul |
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| Concentration | Not Determined |
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| Applications | WB, ELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mbd2 Polyclonal Antibody. • Target Background: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters. |
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| Immunogen | Polyclonal antibody raised in rabbit against mouse MBD2, using a KLH-conjugated synthetic peptide containing an amino acid sequence from the central part of the protein |
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| Other Names | Methyl-CpG-binding domain protein 2, MBD2, DMTase, Methyl-CpG-binding protein MBD2 |
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| Gene, Accession # | Gene ID: 8932, SwissProt: Q9UBB5 |
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| Catalog # | bs-53058R |
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| Price | |
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| Order / More Info | MBD2 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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