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Product Name | Necrostatin-5 |
Description | MW: 383.49. Purity ≥98% by NMR. Background: Inhibits non-apoptotic cell death pathway by inhibition of the death domain receptor-associated adaptor kinase RIP1. Three distinct mechanisms appear to be involved in necroptosis, the alternative active cell death pathway: T-loop dependent inhibition by necrostatin-1; partially T-loop independent inhibition by necrostatin-3 and indirect inhibition of RIP1 by necrostatin-5. |
Size | 5 mg, 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | [3-p-Methoxyphenyl-5,6-tetramethylenothieno[2,3-d]pyrimidin-4-one-2-mercaptoethylcyanide; Nec-5] |
Gene, Accession, CAS # | CAS: 337349-54-9 |
Catalog # | MBS842352 |
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Order / More Info | Necrostatin-5 from MYBIOSOURCE INC. |
Product Specific References | n/a |
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