| 产品详情 |
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| Product Name | Calnexin (CANX) (AA 21-481) protein (His tag) |
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| Description | Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum. Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases.Alternative Names: Calnexin, IP90, Major Histocompatibility Complex Class I Antigen-Binding Protein p88, p90, CANX |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | zgc:63524|wu:fe06b12|clgn|clnx|cnx|CANX|CNX|IP90|P90|canx|1110069N15Rik|AI988026|Cnx|D11Ertd153e|PP90|CG11958|DmelCG11958 |
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| Gene, Accession, CAS # | Gene ID: 821 |
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| Catalog # | ABIN1096189 |
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| Order / More Info | Calnexin (CANX) (AA 21-481) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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